What potential issue could arise when using the PHP syntax in database queries?

One potential issue when using PHP syntax in database queries is the risk of SQL injection attacks if user input is not properly sanitized. To prevent this, it is important to use prepared statements with parameterized queries, which separate the SQL code from the user input, thus preventing malicious SQL code from being executed.

// Example of using prepared statements to prevent SQL injection
$pdo = new PDO('mysql:host=localhost;dbname=mydatabase', 'username', 'password');
$stmt = $pdo->prepare('SELECT * FROM users WHERE username = :username');
$stmt->bindParam(':username', $_POST['username']);
$stmt->execute();