What potential issues can arise when using .htaccess to configure PHP settings?

One potential issue that can arise when using .htaccess to configure PHP settings is that the changes made may not take effect due to server configuration restrictions. To solve this, you can try adding the following code snippet to your .htaccess file to override any server restrictions: ```apache <IfModule mod_php5.c> php_value setting_name value </IfModule> ```