What potential issues can arise when using PHP to handle form submissions and how can they be mitigated?

Issue: One potential issue when handling form submissions in PHP is the vulnerability to SQL injection attacks if user input is not properly sanitized. To mitigate this issue, it is important to use prepared statements when interacting with a database to prevent malicious SQL queries.

// Mitigating SQL injection with prepared statements
$stmt = $pdo->prepare("INSERT INTO users (username, password) VALUES (:username, :password)");
$stmt->bindParam(':username', $username);
$stmt->bindParam(':password', $password);
$stmt->execute();