What is the significance of using different file permission settings (e.g., 777, 644) when trying to manipulate files in PHP scripts?

Using different file permission settings in PHP scripts is significant because it determines who can read, write, and execute the file. For example, setting a file permission of 777 allows anyone to read, write, and execute the file, while setting it to 644 allows only the owner to read and write the file, and others can only read it. It is important to set appropriate file permissions to ensure security and prevent unauthorized access to sensitive files.

// Set file permission to 644
chmod("example.txt", 0644);