What functions and methods in PHP can be used to manipulate file handling and data storage efficiently?

To manipulate file handling and data storage efficiently in PHP, you can use functions like fopen(), fwrite(), fclose(), file_get_contents(), and file_put_contents(). These functions allow you to open files, write data to them, read data from them, and close them properly. By using these functions effectively, you can ensure efficient file handling and data storage in your PHP applications.

// Example of writing data to a file using fwrite()
$file = fopen("data.txt", "w");
fwrite($file, "Hello, World!");
fclose($file);