What are the potential pitfalls of implementing Pop-Up notifications in a PHP web application and how can they be avoided?

Potential pitfalls of implementing Pop-Up notifications in a PHP web application include interrupting the user experience, causing annoyance, and potentially being blocked by browsers' pop-up blockers. To avoid these pitfalls, it is important to use pop-up notifications sparingly and only for important information, provide users with the option to dismiss or disable them, and ensure they are implemented in a way that is compatible with browser settings.

```php
// Example of implementing a pop-up notification with a dismiss button
<?php
if(isset($_SESSION['popup_message'])) {
    echo '<script>alert("' . $_SESSION['popup_message'] . '");</script>';
    unset($_SESSION['popup_message']);
}
?>
```

In this code snippet, we check if a 'popup_message' is set in the session. If it is, we display an alert with the message. This allows the user to see the notification and dismiss it if needed.