What are the potential pitfalls of mixing PHP and JavaScript for data manipulation?

Mixing PHP and JavaScript for data manipulation can lead to potential pitfalls such as code complexity, maintenance difficulties, and security vulnerabilities. To mitigate these risks, it is recommended to separate server-side data manipulation tasks in PHP and client-side interactions in JavaScript to maintain a clear separation of concerns and improve code readability.

<?php
// PHP code for data manipulation
$data = array(1, 2, 3, 4, 5);
$total = array_sum($data);
echo $total;
?>