What are the potential drawbacks of mixing PHP code with HTML in PHP development?

Mixing PHP code with HTML can make the code harder to read and maintain, as it can lead to a messy and convoluted structure. It can also make it more difficult to separate the presentation layer from the business logic, which can hinder code reusability and scalability. To solve this issue, it's recommended to use a templating engine like Twig or Blade, which allows for cleaner separation of PHP logic and HTML presentation.

<?php
// Using Twig templating engine
require_once 'vendor/autoload.php';

$loader = new \Twig\Loader\FilesystemLoader('templates');
$twig = new \Twig\Environment($loader);

echo $twig->render('index.html', ['name' => 'John Doe']);
?>