What are the potential challenges of processing large files in PHP, especially when trying to load them into a MySQL database?

Processing large files in PHP can lead to memory exhaustion and execution time limits, especially when trying to load them into a MySQL database. To mitigate these challenges, one approach is to read the file line by line or in smaller chunks rather than loading the entire file into memory at once. This can help conserve memory usage and prevent script timeouts.

$filename = 'large_file.csv';
$handle = fopen($filename, "r");
if ($handle !== FALSE) {
    while (($data = fgetcsv($handle)) !== FALSE) {
        // Process each line of data here
        // Insert data into MySQL database
    }
    fclose($handle);
}