What are some best practices for handling multiple occurrences of a character in a string in PHP?

When handling multiple occurrences of a character in a string in PHP, one of the best practices is to use the `str_replace()` function to replace all instances of the character with the desired value. This function allows you to specify the character you want to replace and the value you want to replace it with.

$string = "Hello, World!";
$char_to_replace = ",";
$replacement_char = "-";

$new_string = str_replace($char_to_replace, $replacement_char, $string);

echo $new_string; // Output: Hello- World!