What are some best practices for handling ob_buffer in PHP applications?

When working with ob_buffer in PHP applications, it is important to properly handle the output buffering to prevent any unexpected behavior. One best practice is to always check if output buffering is active before starting or flushing it. This can be done using the ob_get_level() function to determine the current level of output buffering.

```php
if (ob_get_level() > 0) {
    ob_end_flush();
}

// Start output buffering
ob_start();
```

This code snippet checks if output buffering is already active and ends it before starting a new output buffer. This helps avoid conflicts and ensures that the output buffer is properly managed in the PHP application.