In what scenarios does output buffering in PHP make a noticeable difference in data transmission speed?

Output buffering in PHP can make a noticeable difference in data transmission speed when dealing with large amounts of data or when sending multiple HTTP headers. By buffering the output, PHP can send the data in larger chunks, reducing the number of network packets sent and improving overall performance. This can be particularly useful when generating dynamic content or when using functions like `header()` to send HTTP headers.

<?php
ob_start(); // Start output buffering

// Your PHP code here to generate content and headers

ob_end_flush(); // Flush the output buffer and send the content to the browser
?>