How can Xdebug be utilized for profiling the server-side performance of a website?

Xdebug can be utilized for profiling the server-side performance of a website by enabling the profiler in the php.ini configuration file and setting up a trigger to generate profiling data. This data can then be analyzed to identify bottlenecks and optimize the code for better performance.

```php
// Enable Xdebug profiler
xdebug.profiler_enable=1
xdebug.profiler_output_dir="/path/to/profiles"

// Set a trigger to generate profiling data
xdebug.profiler_enable_trigger=1
```
Make sure to replace "/path/to/profiles" with the actual path where you want the profiling data to be stored.