How can the use of MySQL be optimized for storing smilie codes and URLs in a PHP guestbook?

To optimize the use of MySQL for storing smilie codes and URLs in a PHP guestbook, you can use a separate table to store the smilie codes and URLs, and then reference them using foreign keys in the guestbook table. This will reduce redundancy and improve data consistency.

```php
// Create a table for storing smilie codes and URLs
CREATE TABLE smilies (
    id INT AUTO_INCREMENT PRIMARY KEY,
    code VARCHAR(10) NOT NULL,
    url VARCHAR(255) NOT NULL
);

// Create a table for the guestbook entries, referencing the smilies table
CREATE TABLE guestbook (
    id INT AUTO_INCREMENT PRIMARY KEY,
    message TEXT,
    smilie_id INT,
    FOREIGN KEY (smilie_id) REFERENCES smilies(id)
);

// Insert smilie codes and URLs into the smilies table
INSERT INTO smilies (code, url) VALUES (':)', 'smilie1.png');
INSERT INTO smilies (code, url) VALUES (':(', 'smilie2.png');
```
This approach allows you to store smilie codes and URLs in a separate table, reducing redundancy and improving data integrity.