How can the structure of a PHP application impact the way file paths are handled in includes and requires?

The structure of a PHP application can impact the way file paths are handled in includes and requires because the paths specified in these statements are relative to the current file's location. To ensure that includes and requires work correctly regardless of the file's location within the application structure, it's essential to use the correct file paths. One way to solve this issue is by using the `__DIR__` constant, which represents the directory of the current file, to construct absolute paths for includes and requires.

// Example of using __DIR__ constant to include a file
require __DIR__ . '/path/to/your/file.php';