How can Subselects be utilized to achieve database-side modifications in WordPress without using wp functions in PHP?

Subselects can be utilized in SQL queries to achieve database-side modifications in WordPress without using wp functions in PHP. By constructing a SQL query with a subselect, you can perform operations like updating, deleting, or inserting data directly within the database. This can be useful when you need to make complex modifications that are not easily achieved using WordPress functions.

global $wpdb;
$wpdb->query("
    UPDATE wp_posts
    SET post_title = 'New Title'
    WHERE ID IN (SELECT post_id FROM wp_postmeta WHERE meta_key = 'custom_key' AND meta_value = 'custom_value')
");