How can PHP handle large file uploads, such as a 500MB PDF file?

When handling large file uploads in PHP, it is important to adjust the PHP configuration settings to allow for larger file sizes. This can be done by increasing the values for `upload_max_filesize`, `post_max_size`, and `max_execution_time` in the php.ini file. Additionally, it is recommended to use a file chunking technique to break the large file into smaller parts and upload them sequentially.

// Adjust PHP configuration settings
ini_set('upload_max_filesize', '500M');
ini_set('post_max_size', '500M');
ini_set('max_execution_time', 300);

// Handle large file upload using chunking technique
// Implement chunking logic here