How can PHP developers effectively handle line breaks and whitespace in email bodies to prevent formatting issues?

To prevent formatting issues with line breaks and whitespace in email bodies, PHP developers can use the PHP function `nl2br()` to convert newline characters to HTML `<br>` tags. This will ensure that line breaks are properly displayed in the email body. Additionally, developers can use the `trim()` function to remove any leading or trailing whitespace from the email content before sending it.

$email_body = "Hello, \n\nThis is a test email.";
$email_body = nl2br(trim($email_body));

// Send email with properly formatted line breaks and no leading/trailing whitespace