How can PHP developers effectively handle file operations, such as reading data in chunks and storing it in a database?

To effectively handle file operations in PHP, developers can read data in chunks using functions like `fread()` and then store it in a database using SQL queries. This approach allows for efficient processing of large files without overwhelming memory usage.

$filename = 'example.txt';
$chunkSize = 1024; // 1KB chunk size

$handle = fopen($filename, 'r');
while (!feof($handle)) {
    $chunk = fread($handle, $chunkSize);
    
    // Store $chunk in the database using SQL query
    
    // Example SQL query:
    // $sql = "INSERT INTO table_name (column_name) VALUES ('$chunk')";
}
fclose($handle);