How can PHP be used to manipulate the quality of images to reduce their file size?

To manipulate the quality of images in PHP to reduce their file size, you can use the `imagejpeg()` function with the quality parameter. By specifying a lower quality value (such as 50), you can reduce the file size of the image while maintaining an acceptable level of visual quality.

// Load the image
$image = imagecreatefromjpeg('input.jpg');

// Save the image with reduced quality
imagejpeg($image, 'output.jpg', 50);

// Free up memory
imagedestroy($image);