How can PHP be used to dynamically load new content on a webpage without using frames?

To dynamically load new content on a webpage without using frames, you can use AJAX (Asynchronous JavaScript and XML) in combination with PHP. AJAX allows you to make asynchronous requests to the server and update parts of the webpage without reloading the entire page. You can create a PHP script that generates the new content based on the request parameters sent via AJAX, and then use JavaScript to update the webpage with the response.

```php
<?php
// check if the request is an AJAX request
if(isset($_SERVER['HTTP_X_REQUESTED_WITH']) && strtolower($_SERVER['HTTP_X_REQUESTED_WITH']) == 'xmlhttprequest') {
    // generate new content based on request parameters
    $newContent = 'This is the new content that was dynamically loaded!';
    
    // return the new content as a JSON response
    echo json_encode(array('content' => $newContent));
    exit;
}
?>
```

This PHP code snippet checks if the request is an AJAX request and generates new content accordingly. The new content is then returned as a JSON response, which can be processed by JavaScript to update the webpage dynamically.