How can functions be organized and managed in PHP to ensure they can be easily reused and accessed?

To ensure functions in PHP can be easily reused and accessed, they can be organized into separate files based on their functionality and then included in the main application file using the `include` or `require` statements. This way, functions can be grouped logically and called whenever needed without duplicating code.

// functions.php
function calculateSum($num1, $num2) {
    return $num1 + $num2;
}

// main.php
require 'functions.php';

$result = calculateSum(5, 10);
echo $result; // Output: 15