Are there best practices for separating PHP code from HTML in web development?

When developing a website using PHP, it is best practice to separate PHP code from HTML to improve code readability, maintainability, and reusability. One common way to achieve this separation is by using PHP templates or a templating engine like Twig. By keeping PHP logic separate from HTML markup, it makes it easier to make changes to the design without affecting the underlying functionality.

<?php
// PHP logic
$variable = "Hello, World!";
?>

<!DOCTYPE html>
<html>
<head>
    <title>PHP Separation Example</title>
</head>
<body>
    <h1><?php echo $variable; ?></h1>
</body>
</html>