Are there any best practices for handling large file sizes in PHP to prevent server connection issues?

Handling large file sizes in PHP can lead to server connection issues due to memory limitations. To prevent this, it's best to use techniques like streaming the file content instead of loading it all into memory at once. One way to achieve this is by using PHP's `readfile()` function, which reads a file and sends it directly to the output buffer without loading it entirely into memory.

$file = 'path/to/large/file';
header('Content-Description: File Transfer');
header('Content-Type: application/octet-stream');
header('Content-Disposition: attachment; filename="'.basename($file).'"');
header('Content-Length: ' . filesize($file));
readfile($file);
exit;